Lu Research Group
Sept. 2022
Our 5th year student Lu Jianhua was awarded the prestigious 2022 ChemStar Award of CCME based on her recent work reporting an interesting aggregation-induce polymerization concept which enabled the synthesis of protein-polydisulfide conjugates under mild conditions. This is her second ChemStar Award after she won the same award first in 2020, great job!
May 24th 2022
Big congratulations to Jialing, who successfully defended her PhD thesis on May 24th. Her research focuses on investigating the long term biosafety and the origin of low immunogenicity of polypeptide-protein conjugates. We will miss her and wish her all the best in the future.
May 2022
This month, we say goodbye to beloved Guangqi, who finished his 7-year journey as a PhD student from 2015 to 2020 and then a postdoc from 2020 to 2022 in the Lu lab. Guangqi will join Dr. Coley's group at MIT as a postdoc soon. We thank him for his time, service, and legacy, and wish him all the best in his new adventure.
Mar. 2022
In this work, we reported the unexpected water-assisted controlled ROP of ProNCA, which affords well-defined PLP as polyproline II helices in 2-5 minutes and almost quantitative yields. Well done, Yali!
https://academic.oup.com/nsr/advance-article/doi/10.1093/nsr/nwac033/6535632
Mar. 2022
In this work, we reviewed the state-of-the-art progresses of α-helical polypeptides for biomedical applications, with a special emphasis on the manipulation of helix-to-coil dynamic transition, conformation-associated anti-biofouling coatings, cellular uptake regulation, and reducing immunogenicity of polypeptide-protein conjugates. Well done, Zhang Chong!
http://www.cjps.org/article/doi/10.1007/s10118-022-2688-2?pageType=en
Oct. 2021
In this work, we developed a moisture-tolerant method enabling the facile synthesis of various challenging amino acid N-carboxyanhydrides, which could eventually greatly facilitate polypeptide preparation. Well done, Ziyou!
https://www.nature.com/articles/s41467-021-25689-y
September 2021
Dr. Lu is a co-organizer of the Young Scholar Symposium and delivered an invited talk.
Dr. Wu, Dr. Xiong, and Dr. Tian each gave a poster.
Dr. Tian Ziyou received the RSC Polymer Chemistry Poster Prize
Ms. Lu Jianhua received the general Best Poster Prize.
Congratulations to all of them!
September 2021
A JACS paper published from our group in 2020 (Lu, J. H. et al. J. Am. Chem. Soc. 2020, 142, 3, 1217-1221; DOI: 10.1021/jacs.9b12937) was recognized and collected in the 2021 JACS Early Career Investigators Virtual Issue!
https://pubs.acs.org/page/jacsat/vi/early-career-investigator2021
June. 2021
Dr. Hu Yali and Dr. Wang Hao, Class of 2016, successfully defended their PHD theses in May 30th and will join Jiangsu Hengrui Pharmaceuticals Co Ltd.
Wang Gan and Zhou Haisen, Class of 2017, received their B.S. in chemistry. Gan will pursue his Ph.D. in NTU at Sigapore and Haisen will continue his PHD research in our group.
Hearty congratulations to all of them!
July. 2021
An intracellular delivery system for His-tagged proteins was developed by Haisen. This is an invited paper for the special issue on "Rising Stars" of Polymer Journal. Hiasen became the first undergraduate in our group to publish a first-author article. Congratulations to him!
https://doi.org/10.1038/s41428-021-00526-7
