Wgroup member: Zhikun Zhang Graduate student (2012.9 ~ present) Current position: Ecole polytechnique fédérale de Lausanne (Xile Hu group); Email: zhangzhk08@126.com; Tel: 18811461223

Education
2008~2012: Lanzhou University; undergraduate study.
2012.9 ~ present: Peking University, graduate student (Jianbo Wang's group)

Ph.D thesis: Application of Carbene Chemistry in The Synthes of Organofluorine Compounds

Publications

(1) Formal Carbon Insertion of N-Tosylhydrazone into B-B and B-Si Bonds: gem-Diborylation and gem-Silylborylation of sp3 Carbon
Huan Li, Xianghang Shangguan, Zhikun Zhang, Shan Huang, Yan Zhang and Jianbo Wang
Org. Lett. 2014, 16, 448-451.

(2) Pd(0)-Catalyzed Cross-Coupling of 1,1-Diboronates with Vinyl Bromides and 1,1-Dibromoalkenes
Huan Li, Zhikun Zhang, Xianghang Shangguan, Shan Huang, Jun Chen, Yan Zhang and Jianbo Wang
Angew. Chem. Int. Ed. 2014, 53, 11921-11925.

(3) Synthesis of Trifluoromethylated Cycloheptatrienes from N-Tosylhydrazones: Transition-Metal-Free Büchner Ring Expansion
Zhikun Zhang, Jiajie Feng, Yan Xu, Songnan Zhang, Yuxuan Ye, Tianjiao Li, Xi Wang,* Jun Chen, Yan Zhang and Jianbo Wang*
Synlett 2015, 26, 59-62. (Invited Contribution for Synlett Cluster on “Progress in Organo-Fluorine Chemistry”)

(4) Cu(I)-Catalyzed Three-Component Coupling of N-Tosylhydrozones, Alkynes and Azides: Synthesis of Trisubstituted 1,2,3-Triazoles
Zhikun Zhang, Qi Zhou, Fei Ye, Ying Xia, Guojiao Wu, Mohammad Lokman Hossain, Yan Zhang, and Jianbo Wang
Adv. Synth. Cat. 2015, 357, 2277-2286. (For special issue dedicated to Prof. Stephen L. Buchwald)

(5) Cu(I)-Catalyzed Cross-Coupling of Terminal Alkynes with Trifluoro-methyl Ketone N-Tosylhydrazones: Access to 1,1-Difluoro-1,3-enynes
Zhikun Zhang, Qi Zhou, Weizhi Yu, Tianjiao Li, Guojiao Wu, Yan Zhang, Jianbo Wang
Org. Lett. 2015, 17, 2474-2477.

(6) Reaction of Diazo Compounds with Difluorocarbene: An Efficient Approach toward 1,1-Difluoroolefins
Zhikun Zhang, Weizhi Yu, Chenggui Wu, Chengpeng Wang, Yan Zhang, Jianbo Wang
Angew. Chem. Int. Ed. 2016, 55, 273-277. (Hot Paper)

(7) Rh(I)-Catalyzed Reaction of Trifluoromethylketone N-Tosylhydrazones and Arylboronates
Zhikun Zhang, Weizhi Yu, Qi Zhou, Tianjiao Li, Yan Zhang and Jianbo Wang
Chin. J. Chem. 2016, 34, 473-476. (Special Issue: Trifluoromethylation and Trifluoromethylthiolation Reactions)

(8) Cu(I)-Catalyzed Stereoselective Synthesis of (E)-a-Alkynyl-a,b-unsaturated Esters from Terminal Alkyne, Diazoesters and Aldehydes
Chenggui Wu, Zhenxing Liu, Zhikun Zhang, Fei Ye, Guisheng Deng, Yan Zhang, and Jianbo Wang
Adv. Synth. Cat. 2016, 358, 2480-2488.(Invited contribution for a thematic issue with the title Base-Metal Catalysis: Mn, Fe, Co, Ni, Cu)

(9) Enantioselective Synthesis of Trisubstituted Allenes via Cu(I)-Catalyzed Coupling of Diazoalkanes with Terminal Alkynes
Wen-Dao Chu, Lei Zhang, Zhikun Zhang, Qi Zhou, Fanyang Mo, Yan Zhang and Jianbo Wang
J. Am. Chem. Soc. 2016, 138, 14558-14561.

(10) Transition metal-catalyzed [2,3]-sigmatropic rearrangements of ylides: an update of the most recent advances
Zhe Sheng, Zhikun Zhang, Changhu Chu, Yan Zhang and Jianbo Wang
Tetrahedron 2017, 73, 4011-4022. (Invited review article)

(11) Palladium-Catalyzed Synthesis of Indoles and Isoquinolines with in-situ Generated Phosphinimine
Qi Zhou, Zhikun Zhang, Yujing Zhou, Shichao Li, Yan Zhang, and Jianbo Wang
J. Org. Chem. 2017, 82, 48-56. (Highlighted by Organic Chemistry Portal)

(12) Cu(I)-Catalyzed Three-Component Coupling of Trifluoromethyl Ketone N-Tosylhydrazones, Alkynes and Azides: Synthesis of Difluoromethylene Substituted 1,2,3-Triazoles
Zhikun Zhang, Qi Zhou, Weizhi Yu, Tianjiao Li, Yan Zhang and Jianbo Wang
Chin. J. Chem. 2017, 35, 387-391. (Special issue dedicated to Prof. Xi-Kui Jiang)

(13) Catalytic asymmetric trifluoromethylthiolation via enantioselective [2,3]-sigmatropic rearrangement of sulfonium ylides
Zhikun Zhang, Zhe Sheng, Weizhi Yu, Guojiao Wu, Rui Zhang, Wen-Dao Chu, Yan Zhang and Jianbo Wang
Nature Chem. 2017, 9, 970-976 (Highlighted by Science China: Chemistry; Highlighted by Angew. Chem. Int. Ed.)

(14) Cu(I)-Catalyzed Stereoselective Doyle-Kirmse Reaction
Zhe Sheng, Ming Ma, Lingling Peng, Zhikun Zhang, Changhu Chu,* Yan Zhang and Jianbo Wang*
Chin. J. Org. Chem. 2017, 37, 1730-1740.