2024

Zhang, S.; Tang, Q.*; Zhang, X.; Chen, X.* “Proximitomics by Reactive Species” ACS Cent. Sci. 10, 1135-1147 (2024).

Lei, C.; Li, X.; Li, W.; Chen, Z.; Liu, S.; Cheng, B.; Hu, Y.; Song, Q.; Qiu, Y.; Zhou, Y.; Meng, X.; Yu, H.; Zhou, W.; Chen, X.*; Li, J.* “Chemical glycoproteomic profiling in rice seedlings reveals N-glycosylation in the ERAD-L machinery” Mol. Cell. Proteomics, 100883 (2024).

Li, S.; Tang, Q.; Jiang, Y.*; Chen, X.* “Inherited glycosylphosphatidylinositol deficiency: a review from molecular and clinical perspectives” Acta Bioch. Bioph. Sin. 56, 1234–1243 (2024).

Xia, X.; Sun, D.; Tang, Q.; Liu, X.; Fan, X.; Wan, Y.; Cui, S.; Zhang, X.; Liu, Q.; Jiang, Y.; Wu, Y.*; Cheng, B.*; Chen, X.* “Fast Metabolic Glycan Labeling for Click-Labeling and Imaging of Sialoglycans in Living Acute Brain Slices from Mice and Human Patients” J. Am. Chem. Soc. 146, 22008–22016 (2024).

Wang, J.; Liu, J.; Huang, R.; Chu, T.; Tang, Q.; Chen, X.* “Proteomic Profiling of Messenger Ribonucleoproteins in Mouse Tissues Based on Formaldehyde Cross-Linking” J. Proteome Res. 23, 1370–1378 (2024).

2023

Xu, C.#; Pan, X.#; Wang, D.; Guan, Y.; Yang, W.; Chen, X.*; Liu, Y.* “ O-GlcNAcylation of Raptor transduces glucose signals to mTORC1” Mol Cell. 83, 3027-3040 (2023).

Tang, Q.; Chen, X.* “ Nascent Proteomics: Chemical Tools for Monitoring Newly Synthesized Proteins” Angew. Chem. Int. Ed. e202305866 (2023).

Liu, J., Cheng, B., Fan, X., Zhou, X., Wang, J., Zhou, W., Li, H., Zeng, W., Yang, P., Chen, X.* “ Click-iG: Simultaneous Enrichment and Profiling of Intact N-linked, O-GalNAc, and O-GlcNAcylated Glycopeptides” Angew. Chem. Int. Ed. 62, e202303410 (2023).

Sun, J.#; Huang, Z.#; Du, Y.#; Lv, P.; Fan, X.; Dai, P.*; Chen, X.* “ Metabolic Glycan Labeling in Primary Neurons Enabled by Unnatural Sugars with No S-Glyco-Modification” ACS Chem. Biol. 18, 1416-1424 (2023).

Zhang, X.#; Tang, Q.#; Sun, J.; Guo, Y.; Zhang, S.; Liang, S.; Dai, P.; Chen, X.* “ Cellular-Scale Proximity Labeling for Recording Cell Spatial Organization in Mouse Tissues” Sci. Adv. 9, eadg6388 (2023).

Hao, Y.#, Li, X.#, Qin, K., Shi, Y., He, Y., Zhang, C., Cheng, B., Zhang, X., Hu, G., Liang, S., Tang, Q., Chen, X.* “ Chemoproteomic and Transcriptomic Analysis Reveals that O-GlcNAc Regulates Mouse Embryonic Stem Cell Fate through the Pluripotency Network” Angew. Chem. Int. Ed. 62, e202300500 (2023).

Li, X.#, Lei, C.#, Song, Q., Bai, L., Cheng, B., Qin, K., Li, X., Ma, B., Wang, B., Zhou, W., Chen, X.*, Li, J.* “ Chemoproteomic profiling of O-GlcNAcylated proteins and identification of O-GlcNAc transferases in rice” Plant Biotechnol. J. 21, 742-753 (2023).

Cheng, B.*#, Wang, C.#, Hao, Y.#, Wang, J., Xia, X., Zhang, H., He, R., Zhang, S., Dai, P., Chen, X.* “ Facile Synthesis of Clickable Unnatural Sugars in the Unprotected and 1,6-Di-O-Acylated Forms for Metabolic Glycan Labeling” Chem. Eur. J. 29, e202203054 (2023).

Liu, W.#; Tang, Q.#; Meng, L.#; Hu, S.; Sun, D.; Li, S.; Dai, P.*; Chen, X.* “ Interbacterial Chemical Communication-Triggered Nascent Proteomics” Angew. Chem. Int. Ed. 62, e202214010 (2023).

2022

Wu, J.; Lei, C.; Li, X.; Dong, X.; Qin, K.; Hong, W.; Li, J.; Zhu, Y.*; Chen, X.* “ Chemoproteomic Profiling of O-GlcNAcylation in Arabidopsis Thaliana by Using Metabolic Glycan Labeling” Isr. J. Chem. 298, e202200065 (2022).

Shi, Y.; Yan, S.; Shao, G.; Wang, J.; Jian, Y.; Liu, B.; Yuan, Y.; Qin, K.; Nai, S.; Huang, X.; Wang, Y.; Chen, Z.; Chen, X.; Dong, M.; Geng, Y.*; Xu, Z.*; Li, J.* “ O-GlcNAcylation Stabilizes the Authophagy-Initiating Kinase ULK1 by Inhibiting Chaperone-Mediated Autophagy upon HPV Infection” J. Biol. Chem. 298, 102341 (2022).

Jin, G.; Sun, D.; Xia, X.; Jiang, Z.; Cheng, B.; Ning, Y.; Wang, Y.; Zhao, Y.*; Chen, X.*; Zhang, J.* “ Bioorthogonal Lanthanide Molecular Probes for Near-Infrared Fluorescence and Mass Spectrometry Imaging” Angew. Chem. Int. Ed. 61, e202208707 (2022).

Lv, P.; Du, Y.; He, C.; Peng, L.; Zhou, X.; Wan, Y.; Zeng, M.; Zhou, W.; Zou, P.; Li, C.; Zhang, M.; Dong, S.*; Chen, X.* “ O-GlcNAcylation modulates liquid–liquid phase separation of SynGAP/PSD-95” Nat. Chem. 14, 831-840 (2022).

Fan, X.; Song, Q.; Sun, D.; Hao, Y.; Wang, J.; Wang, C.; Chen, X.* “ Cell-type-specific labeling and profiling of glycans in living mice” Nat. Chem. Biol. 18, 625-633 (2022).

Zhao, W.; Zhao, S.; Li, Liuju; Huang, X.; Xing, S.; Zhang, Y.; Qiu, G.; Han, Z.; Shang, Y.; Sun, D.; Shan, C.; Wu, R.; Gu, L.; Zhang, S.; Chen, R.; Xiao, J.; Mo, Y.; Wang, J.; Ji, W.; Chen, X.; Ding, B.; Liu, Y,; Mao, H.; Song, B.; Tan, J.; Liu, J.; Li, H.*; Chen, L.* “ Sparse deconvolution improves the resolution of live-cell super-resolution fluorescence microscopy” Nat. Biotechnol. 40, 606-617 (2022).

Cheng, B.*; Wan, Y.; Tang, Q.; Du, Y.; Chen, X.* “ A Photocaged Azidosugar for Light-Controlled Metabolic Labeling of Cell-surface Sialoglycans” Chin. J. Chem. 40, 806-812 (2022).

Liu, J.; Hao, Y.*; Wang, C.; Jin, Y.; Yang, Y.; Gu, J.*; Chen, X.* “ An Optimized Isotopic Photocleavable Tagging Strategy for Site-Specific and Quantitative Profiling of Protein O-GlcNAcylation in Colorectal Cancer Metastasis” ACS Chem. Biol. 17, 513-520 (2022).

Tang, Q.; Liu, L.; Guo, Y.; Zhang, X.; Zhang, S.; Jia, Y.; Du, Y.; Cheng, B.; Yang, L.*; Huang, Y.*; Chen, X.* “ Optical Cell Tagging for Spatially Resolved Single-Cell RNA Sequencing” Angew. Chem. Int. Ed. 61, e202113929 (2022).

2021

Liu, J.; Hao, Y.; He, Y.; Li, X.; Sun, D.; Zhang, Y.; Yang, P.; Chen, X.* “ Quantitative and Site-Specific Chemoproteomic Profiling of Protein O-GlcNAcylation in the Cell Cycle” ACS Chem. Biol. 16, 1917-1923 (2021).

Cheng, B.;Tang, Q.;Zhang, C.; Chen, X.* “ Glycan Labeling and Analysis in Cells and In Vivo” Annu. Rev. Anal. Chem. 14, 363-387 (2021).

Liu, J; Shao, X.; Qin, W.; Zhang, Y.; Dang, F.; Yang, Q.; Yu, X.; Li, Y.; Chen, X.*; Wang, C*; Wang, Y.* “ Quantitative chemoproteomics reveals O-GlcNAcylation of cystathionine γ-lyase (CSE) represses trophoblast syncytialization” Cell Chem. Biol. 28, 788-781 (2021).

Tang, Q.; Guo, Y.; Meng, L.; Chen, X.* “ Chemical Tagging of Protein Lipoylation” Angew. Chem. Int. Ed. 60, 4028-4033 (2021).

Sun, D.; Fan, X.;Shi, Y.; Zhang, H.; Huang, Z.; Cheng, B.; Tang, Q.; Li, W.; Zhu, Y.; Bai, J.; Liu, W.; Li, Y.; Wang, X.; Lei, X.; Chen, X.* “ Click-ExM enables expansion microscopy for all biomolecules” Nat. Methods18, 107-113 (2021).

2020

Meng, L.; Guo, Y.; Tang, Q.; Huang, R.; Xie, Y.; Chen, X.* “ Metabolic RNA labeling for probing RNA dynamics in bacteria” Nucleic Acids Res. 48, 12566-12576 (2020).

Hong, S.; Chen, T.; Liu, L.; Cao, C.; Lv, F.; Rabinowitz, J.D.; Huang, Y.*; Chen, X.* “ Live-Cell Imaging of NADPH Production from Specific Pathways” CCS Chem. 2, 1642-1648 (2020).

Cheng, B.; Chen, X.* “ Chemical Labeling and Analysis of Sialoglycans” Chin. Sci. Bull. 65, 2984-2997 (2020).

Qin, K; Zhang, H.; Zhao, Z.; Chen, X.* “ Protein S-Glyco-Modification Through an Elimination-Addition Mechanism” J. Am. Chem. Soc. 142, 9382-9388 (2020).

Liu, C.; Shi, Y.; Li, J.; Liu, X.; Xiahou, Z.; Tan, Z.; Chen, X.; Li, J.* “ O-GlcNAcylation of Myosin Phosphatase Targeting Subunit 1 (MYPT1) Dictates Timely Disjunction of Centrosomes” J. Biol. Chem. 295, 7341-7349 (2020).

Qin, W.; Xie, Z.; Wang, J.; Ou, G.; Wang, C.*; Chen, X.* “ Chemoproteomic Profiling of O-GlcNAcylation in Caenorhabditis elegans” Biochemistry 59, 3129-3134 (2020).

2019

Cheng, B.; Dong, L.; Zhu, Y.; Huang, R.; Sun, Y.; You, Q.; Song, Q.; Paton, J.C.; Paton, A.W.; Chen, X.* “ 9-Azido Analogs of Three Sialic Acid Forms for Metabolic Remodeling of Cell-Surface Sialoglycans” ACS Chem. Biol. 14， 2141-2147 (2019)

Hao, Y.; Fan, X.; Shi, Y.; Zhang, C.; Sun, D.; Qin, K.; Qin, W.; Zhou, W.; Chen, X.* “ Next-Generation Unnatural Monosaccharides Reveal that ESRRB O-GlcNAcylation Enhances Pluripotency of Mouse Embryonic Stem Cells” Nat. Comm. 10, 4065 (2019).

Qin, W.; Qin, K.; Zhang, Y.; Jia, W.; Chen, Y.; Cheng, B.; Peng, L.; Chen, N.; Liu, Y.; Zhou, W.; Wang, Y.; Chen, X.*; Wang, C.* “ S-Glycosylation-Based Cysteine Profiling Reveals Negative-Feedback Regulation of Glycolysis by Itaconate.” Nat. Chem. Biol. 15, 983-991 (2019).

Wang, W.; Lin, L.; Du, Y.; Song, Y.; Peng, X.; Chen, X.*; Yang, J. C.* “ Assessing the Viability of Transplanted Gut Microbiota by Sequential Tagging with D-Amino Acid-Based Metabolic Probes.” Nat. Comm. 10, 1317 (2019).

Li, Y.; Liu, W.; Tang, Q.; Fan, X.; Hao, Y.; Gao, L.; Li, Z.; Cheng, B.; Chen, X.* “ Gap-Junction-Dependent Labeling of Nascent Proteins in Multicellular Networks.” ACS Chem. Biol. 14, 182-185 (2019).

Gao, L.; Song, Q.; Liang, H.; Zhu, Y.; Wei, T.; Dong, N.; Xiao, J.; Shao, F.; Chen, X.* “ Legionella Effector SetA as A General O-glucosyltransferase for Eukaryotic Proteins.” Nat. Chem. Biol. 15, 213-216 (2019).

2018

Huang, R.; Han, M.; Meng, L.; Chen, X.* “ Capture and Identification of RNA-Binding Proteins By Using Click Chemistry-Assisted RNA-Interactome Capture (CARIC) Strategy” J. Vis. Exp. 140, e58580 (2018).

Liang, L.; Tang, H; Deng, Z.; Liu, Y,; Chen, X.*; Wang, H.* “ Ag Nanoparticles Inhibit the Growth of the Bryophyte, Physcomitrella Patens.” Ecotoxicol. Environ. Saf. 164, 739-748 (2018).

Qin, K.; Zhu, Y; Qin, W.; Gao, J.; Shao, X.; Wang, Y.; Zhou, W.*; Wang, C.*; Chen, X.* “ Quantitiative Profiling of Protein O-GlcNAcylation Sites by an Isotope-Tagged Cleavable Linker” ACS Chem. Biol. 13, 1983-1989 (2018).

Bai, Q.; Dong L.; Hao, Y.; Chen, X.*; Shen, Q.* “ Metabolic Glycan Labeling-Assisted Discovery of Cell-Surface Markers for Primary Neural Stem and Progenitor Cells” Chem. Comm. 54, 5486-5489 (2018).

Huang, R.; Han, M.; Meng, L; Chen, X.* “ Transcriptome-wide discovery of coding and noncoding RNA-binding proteins” Proc. Natl. Acad. Sci. USA 115, E3879-E3887 (2018).

Wang, W.; Chen, X.* “ Antibiotics-Based Fluorescent Probes for Selective Labeling of Gram-Negative and Gram-Positive Bacteria in Living Microbiota” Sci. China Chem. 61, 792-796 (2018).

Xu, Y.; Peng, L.; Wang, S.; Wang, A.; Ma, R.; Zhou, Y.; Yang, J.; Sun, D.; Lin, W.; Chen, X.; Zou, P.* “ Hybrid Indicators for Fast and Sensitive Voltage Imaging” Angew. Chem. Int. Ed. 57, 3949-3953 (2018).

Sun, Y.; Hong, S.; Xie, R.; Huang, R.; Lei, R.; Cheng, B.; Sun, D.; Du, Y.; Nycholat, C.; Paulson, J.; Chen, X.* “ Mechanistic Investigation and Multiplexing of Liposome-Assisted Metabolic Glycan Labeling” J. Am. Chem. Soc. 140, 3592–3602 (2018).

Qin, W.; Qin, K.; Fan, X.; Peng, L.; Hong, W.; Zhu, Y.; Lv, P.; Du, Y.; Huang, R.; Han, M.; Cheng, B.; Liu, Y.; Zhou, W.; Zhou, Y.; Wang, C.*; Chen, X.* “Artificial Cysteine S-Glycosylation Induced by Per-O-Acetylated Unnatural Monosaccharides during Metabolic Glycan Labeling” Angew. Chem. Int. Ed. 57,1817-1820 (2018).

Du, Y.; Xie, R.; Sun, Y.; Fan, X.; Chen, X.* “Liposome-Assisted Metabolic Glycan Labeling with Cell and Tissue Selectivity” Methods Enzymol. 598, 321-353 (2018).

2017

Qin, W.; Lv, P.; Fan, X.; Quan, B.; Zhu, Y.; Qin, K.; Chen, Y.; Wang, C.*; Chen, X.* “Quantitative time-resolved chemoproteomics reveals that stable O-GlcNAc regulates box C/D snoRNP biogenesis” Proc. Natl. Acad. Sci. USA 114, E6749–E6758 (2017).

Wang, W.; Zhu, Y.; Chen, X.* “Selective Imaging of Gram-Negative and Gram-Positive Microbiotas in the Mouse Gut” Biochemistry 56, 3889-3893 (2017).

Zhu, Y.; Chen, X.* “Expanding the Scope of Metabolic Glycan Labeling in Arabidopsis thaliana” ChemBioChem 18, 1286–1296 (2017).

2016

Zhu, Q.; Venzke, D.; Walimbe, A. S.; Anderson, M. E.; Fu, Q.; Kinch, L. N.; Wang, W.; Chen, X.; Grishin, N. V.; Huang, N.; Yu, L.; Dixon, J. E.; Campbell, K. P.*; Xiao J.* “Structure of protein O-mannose kinase reveals a unique active site architecture” ELife 5, e22238 (2016).

Li, Z.; Zhu, Y.; Sun, Y.; Qin, K.; Liu, W.; Zhou, W.; Chen, X.* “Nitrilase-Activatable Noncanonical Amino Acid Precursors for Cell-Selective Metabolic Labeling of Proteomes” ACS Chem. Biol. 11, 3273-3277 (2016).

Zhu, Y.; Wu, J.; Chen, X.* “Metabolic Labeling and Imaging of N-Linked Glycans in Arabidopsis Thaliana” Angew. Chem. Int. Ed 55, 9301-9305 (2016).

Tang, H.; Yang, S.; Yang, Y.; Ke, D.; Liu, J.; Chen, X.; Wang, H.*; Liu, Y.* “Blood Clearance, Distribution, Transformation, Excretion, and Toxicity of Near-Infrared Quantum Dots Ag2Se in Mice” ACS Appl. Mater. Interfaces 8, 17859–17869 (2016).

Xie, R.; Dong, L.; Du, Y.; Zhu, Y.; Hua, R.; Zhang, C.; Chen, X.* “In Vivo Metabolic Labeling of Sialoglycans in the Mouse Brain By Using A Liposome-Assisted Bioorthogonal Reporter Strategy“ Proc. Natl. Acad. Sci. USA 113, 5173-5178 (2016).

Li, H.; Fan, X.; Chen, X.* “Near-Infrared Light Activation of Proteins Inside Living Cells Enabled by Carbon Nanotube-Mediated Intracellular Delivery” ACS Appl. Mater. Interfaces 8, 4500-4507 (2016).

Cheng, B.; Xie, R.; Dong, L. Chen, X.* “Metabolic Remodeling of Cell-Surface Sialic Acids: Principles, Applications, and Recent Advances” ChemBioChem 17, 11-27 (2016).

2015

Lin, W.; Gao, L.; Chen, X.* “Protein-Specific Imaging of O-GlcNAcylation in Single Cells” ChemBioChem 16, 2571-2575 (2015).

Lin, W.; Gao, L.; Chen, X.* “Protein-Specific Imaging of Posttranslational Modifications” Curr. Opin. Chem. Biol. 28, 156-163 (2015).

Du, J.; Hong, S.; Dong, L.; Cheng, B.; Lin, L.; Zhao, B.; Chen, Y.*; Chen, X.* “Dynamic Sialylation in Transforming Growth Factor- β -Induced Epithelial to Mesenchymal Transition” J. Biol. Chem. 290, 12000-12013 (2015).

Lin, L.; Liu, L.; Zhao, B.; Xie, R.; Lin, W.; Li, H.; Shi, M.; Chen, Y.; Springer, T. A.; Chen, X.* “Carbon Nanotube-Assisted Optical Activation of TGF- β Signaling by Near-Infrared Light” Nature Nanotech. 10, 465-471 (2015).

Wang, J.; Cheng, B.; Li, J.; Zhang, Z.; Hong, W.; Chen, X.*; Chen, R. P. “ Chemical Remodeling of Cell-Surface Sialic Acids via Palladium-Triggered Bioorthogonal Elimination Reactions ” Angew. Chem. Int. Ed. 54, 5364-5368 (2015).

Hong, S.; Lin, L.; Xiao, M.; Chen, X.* “Live-Cell Bioorthogonal Raman Imaging” Curr. Opin. Chem. Biol. 24, 91-96 (2015).

2014

Xie, R.; Dong, L.; Huang, R.; Hong, S.; Lei, R.; Chen, X.* “Targeted Imaging and Proteomic Analysis of Tumor-Associated Glycans in Living Animals” Angew. Chem. Int. Ed. 53, 14082-14086 (2014).

Rong, J.; Han, J.; Dong, L.; Tan, Y.; Yang, H.; Feng, L.; Wang, Q.; Meng, R.; Zhao, J.*; Wang, S.*; Chen, X.* “Glycan Imaging in Intact Rat Hearts and Glycoproteomic Analysis Reveal the Upregulation of Sialylation during Cardiac Hypertrophy” J. Am. Chem. Soc. 136, 17468-17476 (2014).

Xiao, M.; Lin, L.; Li, Z.; Liu, J.; Hong, S.; Li, Y.; Zheng, M.; Duan, X.; Chen, X.* “SERS Imaging of Cell-Surface Biomolecules Metabolically Labeled With Bioorthogonal Raman Reporters” Chem. Asian J. 9, 2040-2044 (2014).

Hong, S.; Chen, T.; Zhu, Y.; Li, A.; Huang, Y.*; Chen, X.* “ Live-Cell Stimulated Raman Scattering Imaging of Alkyne-Tagged Biomolecules” Angew. Chem. Int. Ed. 53, 5827-5831 (2014).

Lin, W.; Du, Y.; Zhu, Y.; Chen, X.* “A Cis-Membrane FRET-Based Method for Protein-Specific Imaging of Cell-Surface Glycans” J. Am. Chem. Soc. 136, 679-687 (2014).

2013

Li, S.; Zhang, L.; Yao, Q.; Li L.; Dong, N.; Rong, J.; Gao, W.; Ding, X.; Sun, L.; Chen, X.; Chen, S.*; Shao, F.* “Pathogen Blocks Host Death Receptor Signalling by Arginine GlcNAcylation of Death Domains” Nature 501, 242-246 (2013).

Xie, R.; Hong, S.; Chen, X.* “Cell-selective Metabolic Labeling of Biomolecules with Bioorthogonal Functionalities” Curr. Opin. Chem. Biol. 17, 747-752 (2013).

Feng, L.; Hong, S.; Rong, J.; You, Q.; Dai, P.; Huang, R.; Tan, Y.; Hong, W.; Xie, C.*; Zhao, J.*; Chen, X.* “Bifunctional Unnatural Sialic Acids for Dual Metabolic Labeling of Cell-Surface Sialylated Glycans” J. Am. Chem. Soc. 135, 9244-9247 (2013).

Lin, L.; Tian, X.; Hong, S.; Dai, P.; You, Q.; Wang, R.; Feng, L.; Xie, C.; Tian, Z.*; Chen, X.* “A Bioorthogonal Raman Reporter Strategy for SERS Detection of Glycans on Live Cells.” Angew. Chem. Int. Ed. 52, 7266-7271 (2013).

2012

Zhang, C.; Yin, A.; Jiang, R.; Rong, J.; Dong, L.; Zhao, T.; Sun, L.*; Wang, J.*; Chen, X.*; Yan, C.*; “ Time-Temperature Indicator for Perishable Products Based on Kinetically Programmable Ag Overgrowth on Au Nanorods ” ACS Nano 7, 4561-4568 (2012).

Rouhanifard, S. H.; Xie, R.; Zhang, G.; Sun, X.; Chen, X.*; Wu, P.* “Detection and Isolation of Dendritic Cells Using Lewis X-Functionalized Magnetic Nanoparticles” Biomacromolecules 13, 3039-3045 (2012).

Xie, R.; Hong, S.; Feng, L.; Rong, J.; Chen, X.* “Cell-Selective Metabolic Glycan Labeling Based on Ligand-Targeted Liposomes” J. Am. Chem. Soc. 134, 9914-9917 (2012).

2011

Wang, W.; Hong, S.; Tran, A.; Triano, R.; Jiang, H.; Liu, Y; Chen, X.; Wu, P.* “Sulfated Ligands for the Copper(I)-catalyzed Azide Alkyne Cycloaddition” Chem. Asian J. 6, 2796-2802 (2011).

Hao, Z.; Hong, S.; Chen, X.*; Chen, R. P.* “Introducing Bioorthogonal Functionalities into Proteins in Living Cells ” Acc. Chem. Res. 44, 742-751 (2011).

Prior to PKU

Chen, X.; Yu, Y.; Mi, L.; Walz, T.; Springer, T. A. “Molecular Basis for Complement Recognition by Integrin αXβ2” Proc. Natl. Acad. Sci. USA 109, 4586-4591 (2012).

Shi, M.; Zhu, J.; Wang, R.; Chen, X.; Mi, L.; Walz, T.; Springer, T. A. “Latent TGF-β Structure and Activation ” Nature 474, 343-349 (2011).

Chen, X.; Xie, C.; Nishida, N.; Li, Z.; Walz, T.; Springer, T. A. “Requirement of Open Headpiece Conformation for Activation of Leukocyte Integrin αXβ2” Proc. Natl. Acad. Sci. USA 107, 14727-14732 (2010).

Xie, C; Zhu, J.; Chen, X.; Lizhi Mi; Nishida, N.; Springer, T. A. “Structure of an integrin with an αI domain, complement receptor type 4” EMBO J. 29, 666-678 (2010).

Chang, P.; Chen, X.; Smyrniotis, C.; Xenakis, A.; Hu, T; Bertozzi, C. R.; Wu, P.; “Metabolic Labeling of Sialic Acids in Living Animals with Alkynyl Sugars” Angew. Chem. Int. Ed. 48, 4030-4033 (2009).

Chen, X.; Wu, P.; Rousseas, M.; Okawa, D.; Gartner, Z.; Zettl, A.; Bertozzi, C. R. “Boron Nitride Nanotubes Are Noncytotoxic and Can Be Functionalized for Interaction with Proteins and Cells” J. Am. Chem. Soc. 131, 890-891 (2009).

Wu, P.; Chen, X.; Hu, N.; Tam, U. C.; Blixt, O.; Zettl, A.; Bertozzi, C. R. “Biocompatible Carbon Nanotubes Generated by Functionalization with Glycodendrimers” Angew. Chem. Int. Ed. 47, 5022-5055 (2008).

Chen, X.; Kis, A.; Zettl, A.; Bertozzi, C. R. “A Cell Nanoinjector Based on Carbon Nanotubes” Proc. Natl. Acad. Sci. USA 104, 8218-8222 (2007).

Rabuka, D.; Parthasarathy, R.; Lee, G. S.; Chen, X.; Groves, J. T.; Bertozzi, C. R. “Hierarchical Assembly of Model Cell Surfaces: Synthesis of Mucin Mimetic Polymers and their Display on Supported Bilayers” J. Am. Chem. Soc. 129, 5462-5471 (2007).

Chen, X.; Tam, U. C.; Czlapinski, J. L.; Lee G. S.; Rabuka, D.; Zettl, A.; Bertozzi, C. R. “Interfacing Carbon Nanotubes with Living Cells” J. Am. Chem. Soc. 128, 6292-6293 (2006).

Chen, X.; Lee G. S.; Zettl A.; Bertozzi, C. R. “Biomimetic Engineering of Carbon Nanotubes Using Cell Surface Mucin Mimics” Angew. Chem. Int. Ed. 43, 6111-6116 (2004).

Sun, X.; Chen, X.; Li, Y. “A CTAB-Assisted Hydrothermal Orientation Growth of ZnO Nanorods” Mater. Chem. Phys. 78, 99-104 (2003).

Sun, X.; Chen, X.; Li, Y. “Large-Scale Synthesis of Sodium and Potassium Titanate” Inorg. Chem. 41, 4996-4998 (2002).

Sun, X.; Chen, X.; Li, Y. “Evaporation Growth of Multipod ZnO Whisker Assisted by A Cu2+ Etching Technique” J. Crystal. Growth. 244, 218-223 (2002).

Chen, X.; Sun, X.; Li, Y. “Self-Assembling Vanadium Oxide Nanotubes by Organic Molecular Templates” Inorg. Chem. 41, 4524-4530 (2002).

Chen, X.; Deng, Z.; Li, Y.; Li, Y. “Hydrothermal Synthesis and Superparamagnetic Behaviors of A Series of Ferrite Nanoparticles” Chin. J. Inorg. Chem. 18, 460-464 (2002).